Regulation at the post-transcription level is of critical importance for the fast adaptation of bacterial pathogens to their host environment. Small non-coding RNAs and the RNA chaperone Hfq are major players in this fast adaptation. Here we briefly present mechanisms used by sRNAs and Hfq to regulate gene expression at the post-transcription level, together with results from our research on sRNAs and Hfq-like proteins from Burkholderia cepacia complex bacteria.
Artigo por Christian Ramos, André Grilo, Sílvia Sousa, Joana Feliciano,Jorge Leitão. Faça o download aqui.