Yeast as model Eukaryote and expression host system

The role of the Yeast Saccharomyces cerevisiae as model eukaryote has been questioned in the last few years, given the increased ability to conduct research in more complex eukaryotes, including man. In this paper, the usefulness of budding yeast as a model eukaryote is discussed, highlighting the assets that still make S. cerevisiae a powerful system, both as a single-cell eukaryotic model organism and as a host for the functional analysis of heterologous proteins. As a case-study, the use of Yeast to uncover the mechanisms of resistance against stresses relevant in Plant Biology and Biotechnology and to characterize the role of plant membrane transporters, which were found to be important in this context, is considered.

Artigo por Teixeira MC, Cabrito TR, Brazão J, Sá-Correia I. Faça o download aqui. 

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